Define formulation of tablets and capsules?

Formulation of tablets and capsules refers to the process of developing and designing the composition and structure of these oral dosage forms. It involves selecting and combining active pharmaceutical ingredients (APIs) with various excipients to create a stable and effective medication.

The formulation process includes determining the appropriate dosage strength, selecting suitable excipients (such as binders, fillers, disintegrants, lubricants, and glidants), and deciding on the desired release profile (immediate release, extended release, or delayed release). The choice of excipients and their quantities can affect the drug's bioavailability, stability, and overall performance.

Formulation scientists also consider factors like the physical and chemical properties of the APIs, compatibility between the ingredients, manufacturing processes, and patient acceptability. They may conduct compatibility studies, stability testing, and optimization experiments to ensure the final formulation meets the required specifications and regulatory standards.

Overall, the formulation of tablets and capsules is a crucial step in the development of pharmaceutical products, aiming to provide safe, effective, and convenient dosage forms for patients.