Describe 15 commonly used excipients used in tablets and functions?
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ChatGPT
13 hours ago
1. Microcrystalline cellulose: Acts as a binder, disintegrant, and filler in tablets. 2. Lactose: Acts as a filler, binder, and diluent in tablets. 3. Magnesium stearate: Acts as a lubricant and helps in the release of tablets from molds. 4. Croscarmellose sodium: Acts as a super disintegrant in tablets. 5. Povidone: Acts as a binder and disintegrant in tablets. 6. Sodium starch glycolate: Acts as a super disintegrant in tablets. 7. Hydroxypropyl cellulose: Acts as a binder and disintegrant in tablets. 8. Polyethylene glycol: Acts as a binder and lubricant in tablets. 9. Talc: Acts as a glidant and lubricant in tablets. 10. Silicon dioxide: Acts as a glidant and anti-caking agent in tablets. 11. Polyvinyl alcohol: Acts as a binder and film-forming agent in tablets. 12. Hypromellose: Acts as a binder and film-forming agent in tablets. 13. Stearic acid: Acts as a lubricant and helps in the release of tablets from molds. 14. Ethyl cellulose: Acts as a binder and film-forming agent in tablets. 15. Sorbitol: Acts as a sweetener and filler in tablets.
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Google Gemini AI
13 hours ago
1. Binders: Hold the tablet together once compressed. Examples include: - Cellulose derivatives (microcrystalline cellulose, hydroxypropyl cellulose) - Starch (pregelatinized starch, corn starch) - Gelatin
2. Disintegrants: Promote tablet breakdown in the body. Examples include: - Cross-linked carboxymethylcellulose - Sodium starch glycolate - Croscarmellose sodium
3. Lubricants: Reduce friction during manufacturing and enhance tablet flow and ejection. Examples include: - Stearic acid - Magnesium stearate - Talc
5. Fillers: Add bulk to the tablet and reduce the amount of active ingredient needed. Examples include: - Lactose - Mannitol - Microcrystalline cellulose
6. Colors: Provide color and help distinguish tablets. Examples include: - D&C Red No. 27 - FD&C Blue No. 1 - Iron oxide
7. Flavors: Mask unpleasant tastes or enhance palatability. Examples include: - Artificial strawberry - Chocolate - Mint
14. Thickeners: Increase the viscosity of liquid formulations. Examples include: - Xanthan gum - Guar gum - Carbomer
15. Sustained-release agents: Control the release of the active ingredient over a period of time. Examples include: - Ethylcellulose - Hydroxypropyl methylcellulose - Methacrylic acid copolymers