Artane (trihexyphenidyl) is a medication used to treat symptoms of Parkinson's disease and other movement disorders. It works by blocking the action of acetylcholine, a neurotransmitter in the brain that is involved in muscle control.
The pharmacological table of Artane includes the following information:
- Drug class: Anticholinergic agent - Mechanism of action: Blocks the action of acetylcholine at muscarinic receptors in the brain, leading to a reduction in tremors, muscle stiffness, and other symptoms of Parkinson's disease - Indications: Treatment of Parkinson's disease, drug-induced extrapyramidal symptoms, and other movement disorders - Dosage forms: Tablets, capsules, and liquid solution - Dosage: The usual starting dose for adults is 1-2 mg taken 3-4 times daily, with the dose gradually increased as needed to a maximum of 15 mg per day - Side effects: Common side effects include dry mouth, blurred vision, constipation, and urinary retention. More serious side effects can include confusion, hallucinations, and difficulty breathing - Contraindications: Artane should not be used in patients with glaucoma, myasthenia gravis, or a history of hypersensitivity to trihexyphenidyl - Drug interactions: Artane may interact with other medications that have anticholinergic effects, such as certain antidepressants, antihistamines, and antipsychotics
It is important to follow the dosing instructions provided by a healthcare provider and to report any side effects or concerns while taking Artane.