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Ribo-Seq, also referred to as ribosome profiling or ribosome footprinting, is a next-generation sequencing (NGS)-based transcriptomic research technique that measures translation comprehensively and quantitatively. Ribo-Seq detected the precise positions of ribosomes to determine which mRNAs are being actively translated, which allows for the profiling of the active ribosomes in a cell at a particular moment, as well as the location of the translation initiation sites, the complement of translated ORFs, the specific locations of ribosomes on the mRNA, and the translation rate of ribosomes. ribo seq analysis
a full range of RNA sequencing services to help analyze the gene expression patterns, examine changes in the transcriptome, and detect novel RNA molecules, mutations, and gene fusions, enabling a deeper understanding of RNA biology and disease development. In addition to NGS, we provide a long-read sequencing-based method (iso-seq) for full-length transcript sequencing, avoiding errors that can occur with NGS approaches. rna seq data
professional SMRT-based microbial epigenomics service to analyze the frequency and distribution of methylated residues in microbial genomes. epigenetics bacterial dna methylation gets smrt
CD Genomics is now providing nanopore direct RNA ( direct cDNA or direct RNA)sequencing to achieve the ultimate goal of a comprehensive and bias-free understanding of transcriptomes. With years of experience in long-read RNA-seq analysis and advanced ONT platforms, we will be your best partner for direct RNA-seq. nanopore direct rna sequencing
A provider of metagenomics data analysis, CD Genomics uses bioinformatics to help you solve the problems related to environmental microbiology in one stop. Our unique data analysis skills can also meet customers' personalized data analysis needs. We will provide you with a high-quality data analysis platform, a fast analysis cycle and a high-quality result report. metagenomics bioinformatics
CD Genomics uses a mature high-throughput sequencing platform combined with epigenetics to provide a variety of biological information analysis services, such as genome-wide epigenetic positioning analysis and genes research on expression regulation mechanism. We will provide you with a clear and reliable report of epigenetic analysis result. epigenetics bioinformatics
As a leading provider of NGS services and a partner of Illumina, CD Genomics offers a portfolio of solutions for metagenomics sequencing. 16S/18S/ITS amplicon sequencing is characterized by cost-efficiency, high-speed and practicability to help you identify and investigate the microbial community. With over 10 years of experience, we can totally meet your project requirements and budgets in the exploration of microbial biodiversity. 16s rrna
Glycosylation, the process of attaching glycans to proteins or other organic molecules, is one of the most common post-translational modifications (PTMs). Glycans are highly branched carbohydrate structures, consisting of monosaccharide sugars, such as fucose, galactose, manose, sialic acid, and N-acetylglucosamine. Due to the complexity and diversity of composition and structure of glycans, and the site of glycan attachment, glycosylation may affect product stability, immunogenicity, serum clearance, pharmacokinetics, and anti-inflammatory activity. Therefore, glycosylation is a Critical Quality Attribute (CQA) that must be presented. Glycosylation analysis is critical step to ensure safety and potency of biopharmaceutical products during the process of drug discovery. prediction of n glycosylation sites in human proteins
The special N-glycosylation structure is related to the safety and effectiveness of many protein drugs. Determining the exact N-glycan site occupancy can be used to comprehensively analyze the glycosylation of proteins, therefore, the measurement and analysis of N-glycan sites is an important biochemical technology for biopharmaceutical development projects. The technical method can be used to determine the type and content of N-glycosylation sites of biopharmaceutical proteins or other biological agents, determine the structure and relative content of glycosylation, and also measure free N-glycans. n glycan analysis
Based on gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) technologies, Creative Proteomics provides fast and accurate qualitative and quantitative analysis of fatty acids and derivatives to meet your different needs. phospholipid fatty acid analysis
Acenocoumarol is an anticoagulant that is being developed to prevent complications associated with atrial fibrillation, prosthetic heart valves, and thromboembolic diseases such as deep vein thrombosis and pulmonary embolism. Creative Proteomics can provide you with acenocumarol content testing based on high performance liquid chromatography-mass spectrometry (HPLC-MS/MS) technology. acenocoumarol
comprehensive PS targeted lipidomics services from lipid extraction, lipid detection and data analysis for biomedical research institutions, biotechnology and pharmaceutical companies. phosphatidylserine assay hplc
Creative Proteomics uses Progenesis QI (Waters) and LipidSearch (Thermo) and MS DIAL for our Lipidomics Statistics. lipidomics data analysis
There are three levels of protein interactions: multi-subunit proteins, multi-component protein complexes, and transient, ordered associations between different proteins. In particular, the last protein interaction exists widely in living organisms and plays a role in various life activities such as material metabolism, signal transduction, cell growth and death. Commonly used methods to study protein interactions are: tandem affinity purification, co-immunoprecipitation, yeast two hybrid, phage display and chemical cross-linking, etc. XLMS
Eicosanoids include prostaglandins (PG), thromboxanes (TX), leukotrienes (LT), and lipoxins (LX). Prostanoids refer to PGs and TXs. The names of prostanoids are given according to the number of carbon-carbon double bonds in the molecule. Because of the presence of two carbon-carbon double bonds, most of the biologically active prostaglandins and thromboxanes are series 2 molecules. The eicosanoids with four carbon-carbon double bonds are series 4 molecules. Eicosanoids