Give reason why erythromycin is contraindicated in asthmatic patient theophylline??????

Erythromycin is contraindicated in asthmatic patients who are taking theophylline because erythromycin can inhibit the metabolism of theophylline, leading to increased levels of theophylline in the blood. This can result in toxicity symptoms such as nausea, vomiting, seizures, and cardiac arrhythmias. Therefore, the combination of erythromycin and theophylline should be avoided in asthmatic patients to prevent these potentially serious adverse effects.