Difference between direct bilirubin and indirect bilirubin?

Direct bilirubin, also known as conjugated bilirubin, is a form of bilirubin that has been processed by the liver and is water-soluble. It is excreted in the bile and eventually eliminated from the body through the feces. Elevated levels of direct bilirubin may indicate liver disease or bile duct obstruction.

Indirect bilirubin, also known as unconjugated bilirubin, is a form of bilirubin that has not yet been processed by the liver. It is insoluble in water and is carried in the bloodstream to the liver, where it is converted into direct bilirubin. Elevated levels of indirect bilirubin may indicate conditions such as hemolytic anemia or Gilbert's syndrome.