What genotypes may end up giving birth to sickle cell?
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Mar 8
The genotypes that may result in sickle cell disease are:
1. Homozygous for the sickle cell gene (HbSS): In this case, both parents carry the sickle cell gene, resulting in a child with sickle cell disease.
2. Heterozygous for the sickle cell gene (HbAS): In this case, one parent carries the sickle cell gene and the other parent carries a normal hemoglobin gene. This results in a child with sickle cell trait, which is a carrier of the sickle cell gene but does not have the disease. If two individuals with sickle cell trait have a child, there is a 25% chance that the child will have sickle cell disease.