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Jan 30

# What are four superfamily receptors? ?

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Jan 30
1. G protein-coupled receptors (GPCRs): These receptors are involved in a wide range of physiological processes and are the largest superfamily of receptors. They are involved in signal transduction across the cell membrane and are targeted by a large number of drugs.

2. Ligand-gated ion channels: These receptors are involved in the transmission of signals across the cell membrane by allowing the passage of ions in response to the binding of specific ligands. Examples include the nicotinic acetylcholine receptor and the glutamate receptor.

3. Receptor tyrosine kinases (RTKs): These receptors are involved in cell signaling and regulation of cell growth, differentiation, and survival. They have an intrinsic enzymatic activity that phosphorylates tyrosine residues in response to ligand binding. Examples include the epidermal growth factor receptor (EGFR) and the insulin receptor.

4. Nuclear hormone receptors: These receptors are located in the cell nucleus and are involved in the regulation of gene expression. They bind to specific hormone molecules and act as transcription factors, modulating the expression of target genes. Examples include the estrogen receptor and the glucocorticoid receptor.
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