Symptoms of down syndrome?

Some common symptoms of Down syndrome include:

1. Intellectual disability
2. Delayed development, such as delayed speech and motor skills
3. Low muscle tone
4. Flat facial features
5. Small head and ears
6. Short stature
7. Upward slanting eyes
8. Single deep crease across the center of the palm
9. Heart defects
10. Hearing and vision problems
11. Thyroid problems
12. Increased risk of certain medical conditions, such as leukemia and Alzheimer's disease.

Facial Features:

- Round face
- Small head
- Short or upturned nose with a wide, flattened bridge
- Enlarged tongue
- Widely spaced eyes with an epicanthal fold (skin fold over the inner corner of the eye)

Head and Neck:

- Microcephaly (small head circumference)
- Brachycephaly (short, wide skull)
- Short, broad neck with excess skin

Limbs and Musculoskeletal:

- Short stature
- Short, broad hands
- Single palmar crease (horizontal line on the palm)
- Hyperflexibility in joints
- Flat feet

Intellectual Disability:

- Mild to severe intellectual disability (IQ below 70)
- Language and speech delays
- Difficulty with learning and problem-solving
- Behavioral issues, such as impulsivity and tantrums

Health Conditions:

- Congenital heart defects (e.g., atrial septal defect)
- Gastrointestinal problems (e.g., Hirschsprung's disease)
- Thyroid disorders (e.g., hypothyroidism)
- Obesity
- Leukemia (increased risk)

Other Symptoms:

- Dry skin
- Thin hair
- Epicanthal folds (in both eyes)
- Sparse eyelashes
- Brushfield spots (white or yellow spots on the iris)
- Short, deep palmar creases
- Hand anomalies (e.g., ulnar loop, fifth finger clinodactyly)
- Hypotonia (low muscle tone)
- Sleep apnea
- Vision problems (e.g., strabismus, nystagmus)