In-vivo gene therapy?

In-vivo gene therapy refers to a type of gene therapy that involves directly delivering therapeutic genes into the body of a living organism. This is done by using vectors, such as viruses or non-viral delivery systems, to introduce the therapeutic genes into the target cells of the patient.

In this approach, the therapeutic genes are typically delivered to the target cells within the body, rather than ex vivo gene therapy where cells are taken out of the body, modified in the laboratory, and then reintroduced into the patient.

In-vivo gene therapy has the advantage of being less invasive and more convenient compared to ex vivo gene therapy. It can be used to treat a wide range of genetic disorders, including inherited diseases, by correcting or replacing the faulty genes within the patient's cells.

However, in-vivo gene therapy also presents challenges such as efficient delivery of the therapeutic genes to the target cells, avoiding immune responses against the vectors, and ensuring the long-term stability and expression of the introduced genes. Ongoing research and advancements in gene delivery techniques are being conducted to overcome these challenges and improve the effectiveness of in-vivo gene therapy.