Factors associated with fatty liver disease.

1. Obesity: Excess body weight, particularly around the abdomen, is a major risk factor for fatty liver disease.

2. Insulin resistance: When the body's cells become resistant to the effects of insulin, it can lead to an accumulation of fat in the liver.

3. Type 2 diabetes: People with diabetes are at an increased risk of developing fatty liver disease.

4. High levels of triglycerides in the blood: Elevated levels of triglycerides, a type of fat in the blood, can contribute to fatty liver disease.

5. Metabolic syndrome: This cluster of conditions, including high blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol levels, is associated with an increased risk of fatty liver disease.

6. Poor diet: Consuming a diet high in sugar, refined carbohydrates, and unhealthy fats can contribute to the development of fatty liver disease.

7. Sedentary lifestyle: Lack of physical activity can lead to weight gain and increase the risk of fatty liver disease.

8. Genetics: Some people may be more predisposed to developing fatty liver disease due to genetic factors.

9. Rapid weight loss: Losing weight too quickly can lead to the release of stored fat in the liver, increasing the risk of fatty liver disease.

10. Alcohol consumption: Excessive alcohol consumption can cause fatty liver disease, known as alcoholic fatty liver disease.

Metabolic Factors:

- Obesity (BMI ≥ 30 kg/m²)
- Insulin resistance or type 2 diabetes
- Dyslipidemia (elevated triglycerides, low HDL cholesterol)
- Metabolic syndrome

Genetic Factors:

- Family history of fatty liver disease
- Polymorphisms in genes involved in lipid metabolism (e.g., PNPLA3, TM6SF2)

Dietary Factors:

- High-fat diet (especially saturated and trans fats)
- Excessive fructose intake (e.g., sugary drinks)

Lifestyle Factors:

- Sedentary lifestyle
- Alcohol consumption
- Smoking

Other Associated Conditions:

- Non-alcoholic steatohepatitis (NASH)
- Pregnancy
- Celiac disease
- Wilson's disease
- Hemochromatosis
- Autoimmune hepatitis

Specific Risk Factors for Different Types of Fatty Liver Disease:

Non-Alcoholic Fatty Liver Disease (NAFLD):

- Obesity
- Diabetes
- Metabolic syndrome

Alcoholic Fatty Liver Disease (AFLD):

- Excessive alcohol consumption

Drug-Induced Fatty Liver Disease:

- Medications (e.g., amiodarone, corticosteroids)
- Herbal supplements

Other Factors:

- Age (risk increases with age)
- Sex (men are more likely to develop fatty liver disease)
- Race/ethnicity (higher rates in Hispanic and Asian populations)