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Jun 29
Hydrocortisone is a type of corticosteroid medication that is used to reduce inflammation and relieve symptoms such as itching, redness, and swelling. It is commonly used to treat skin conditions such as eczema, dermatitis, and insect bites. Hydrocortisone can be found in various forms, including creams, ointments, and lotions, and is available over-the-counter or by prescription. It is important to follow the instructions provided by your healthcare provider or on the product label when using hydrocortisone to ensure safe and effective treatment.
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Google Gemini AI
Jun 29
Hydrocortisone
Class: Glucocorticoid
Mechanism of Action:
- Binds to glucocorticoid receptors, thereby enhancing receptor activity
- Inhibits pro-inflammatory cytokine production
- Promotes anti-inflammatory effects
- Suppresses immune responses
Indications:
- Topical:
- Allergic and inflammatory skin conditions (e.g., eczema, psoriasis, dermatitis)
- Bites, stings, and rashes
- Sunburn
- Systemic:
- Allergic reactions (e.g., anaphylaxis)
- Severe inflammatory conditions (e.g., lupus, rheumatoid arthritis, inflammatory bowel disease)
- Endocrine disorders (e.g., adrenal insufficiency)
- Immunosuppressant therapy
Dosage:
- Varies depending on indication and route of administration
- Topical: Apply a thin layer to affected area once or twice daily
- Systemic: Oral, intravenous, or intramuscular administration
Side Effects:
Topical:
- Skin irritation, dryness, or burning
- Thinning of skin
- Increased susceptibility to infections
- Acne or rosacea (with prolonged use)
Systemic:
- Fluid retention (edema)
- Elevated blood sugar levels
- Suppression of the adrenal system
- Weight gain
- Mood changes
- Increased risk of infections
- Osteoporosis (with long-term use)
Contraindications:
- Hypersensitivity to hydrocortisone
- Systemic infections
- Active peptic ulcers
- Severe heart failure
Precautions:
- Use with caution in patients with diabetes, hypertension, or liver or kidney disease
- Prolonged use of systemic hydrocortisone may require gradual tapering of dosage
- Avoid use of topical hydrocortisone on children under 2 years of age
Class: Glucocorticoid
Mechanism of Action:
- Binds to glucocorticoid receptors, thereby enhancing receptor activity
- Inhibits pro-inflammatory cytokine production
- Promotes anti-inflammatory effects
- Suppresses immune responses
Indications:
- Topical:
- Allergic and inflammatory skin conditions (e.g., eczema, psoriasis, dermatitis)
- Bites, stings, and rashes
- Sunburn
- Systemic:
- Allergic reactions (e.g., anaphylaxis)
- Severe inflammatory conditions (e.g., lupus, rheumatoid arthritis, inflammatory bowel disease)
- Endocrine disorders (e.g., adrenal insufficiency)
- Immunosuppressant therapy
Dosage:
- Varies depending on indication and route of administration
- Topical: Apply a thin layer to affected area once or twice daily
- Systemic: Oral, intravenous, or intramuscular administration
Side Effects:
Topical:
- Skin irritation, dryness, or burning
- Thinning of skin
- Increased susceptibility to infections
- Acne or rosacea (with prolonged use)
Systemic:
- Fluid retention (edema)
- Elevated blood sugar levels
- Suppression of the adrenal system
- Weight gain
- Mood changes
- Increased risk of infections
- Osteoporosis (with long-term use)
Contraindications:
- Hypersensitivity to hydrocortisone
- Systemic infections
- Active peptic ulcers
- Severe heart failure
Precautions:
- Use with caution in patients with diabetes, hypertension, or liver or kidney disease
- Prolonged use of systemic hydrocortisone may require gradual tapering of dosage
- Avoid use of topical hydrocortisone on children under 2 years of age
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