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Nov 24, 2023

How does mutation work?

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Nov 24, 2023
Mutation is a process that introduces changes or alterations in the DNA sequence of an organism. It can occur naturally or be induced by external factors such as radiation, chemicals, or errors during DNA replication.

There are different types of mutations, including point mutations, insertions, deletions, duplications, and inversions. Point mutations involve the substitution of a single nucleotide base with another, which can result in different amino acids being coded for during protein synthesis. Insertions and deletions involve the addition or removal of nucleotide bases, respectively, which can cause a shift in the reading frame and alter the entire protein sequence. Duplications occur when a segment of DNA is copied multiple times, leading to an increased number of genes. Inversions involve the reversal of a DNA segment's orientation.

Mutations can occur in somatic cells or germ cells. Somatic mutations are acquired during an organism's lifetime and are not passed on to offspring. These mutations can lead to diseases like cancer. Germ cell mutations, on the other hand, occur in reproductive cells and can be passed on to future generations.

The effects of mutations can vary. Some mutations are neutral and have no significant impact on the organism. Others can be beneficial, providing an advantage in certain environments or leading to the evolution of new traits. However, mutations can also be harmful, causing genetic disorders or reducing an organism's fitness.

Overall, mutation is a fundamental process in the evolution of species, as it introduces genetic diversity and provides the raw material for natural selection to act upon.
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