Anonymous
Jan 8
Give life cycle of plasmodium ovale ?
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Jan 8
The life cycle of Plasmodium ovale, a species of malaria parasite, involves both human and mosquito hosts. Here is a simplified version of its life cycle:
1. Infection: The life cycle begins when an infected female Anopheles mosquito bites a human and injects sporozoites, the infective stage of the parasite, into the bloodstream.
2. Liver stage: The sporozoites travel to the liver and invade hepatocytes (liver cells). Inside the hepatocytes, they undergo asexual reproduction, forming thousands of merozoites.
3. Blood stage: The merozoites are released from the liver cells and enter the bloodstream, where they invade red blood cells (RBCs). Inside the RBCs, they undergo further asexual reproduction, resulting in the release of more merozoites.
4. Fever and symptoms: As the infected RBCs rupture, releasing merozoites, the person experiences recurrent episodes of fever, chills, and other symptoms associated with malaria.
5. Gametocytes: Some of the merozoites differentiate into male and female gametocytes, the sexual stage of the parasite. These gametocytes are taken up by a mosquito when it feeds on the infected person's blood.
6. Mosquito stage: Inside the mosquito's gut, the male and female gametocytes fuse to form a zygote, which develops into a motile form called an ookinete. The ookinete penetrates the mosquito's gut wall and forms an oocyst.
7. Sporogony: Inside the oocyst, the parasite undergoes multiple rounds of division, resulting in the formation of thousands of sporozoites.
8. Transmission: The sporozoites migrate to the mosquito's salivary glands. When the mosquito bites another human, it injects these sporozoites into the bloodstream, starting the cycle again.
It is important to note that the life cycle of Plasmodium ovale can vary slightly from other species of Plasmodium, such as Plasmodium falciparum or Plasmodium vivax.
1. Infection: The life cycle begins when an infected female Anopheles mosquito bites a human and injects sporozoites, the infective stage of the parasite, into the bloodstream.
2. Liver stage: The sporozoites travel to the liver and invade hepatocytes (liver cells). Inside the hepatocytes, they undergo asexual reproduction, forming thousands of merozoites.
3. Blood stage: The merozoites are released from the liver cells and enter the bloodstream, where they invade red blood cells (RBCs). Inside the RBCs, they undergo further asexual reproduction, resulting in the release of more merozoites.
4. Fever and symptoms: As the infected RBCs rupture, releasing merozoites, the person experiences recurrent episodes of fever, chills, and other symptoms associated with malaria.
5. Gametocytes: Some of the merozoites differentiate into male and female gametocytes, the sexual stage of the parasite. These gametocytes are taken up by a mosquito when it feeds on the infected person's blood.
6. Mosquito stage: Inside the mosquito's gut, the male and female gametocytes fuse to form a zygote, which develops into a motile form called an ookinete. The ookinete penetrates the mosquito's gut wall and forms an oocyst.
7. Sporogony: Inside the oocyst, the parasite undergoes multiple rounds of division, resulting in the formation of thousands of sporozoites.
8. Transmission: The sporozoites migrate to the mosquito's salivary glands. When the mosquito bites another human, it injects these sporozoites into the bloodstream, starting the cycle again.
It is important to note that the life cycle of Plasmodium ovale can vary slightly from other species of Plasmodium, such as Plasmodium falciparum or Plasmodium vivax.
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