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Buruhani Swaibu
more than 2 weeks ago

Explain how pulmonary edema occurs

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ChatGPT
more than 2 weeks ago
Pulmonary edema occurs when there is an abnormal accumulation of fluid in the lungs. This can happen due to various reasons, including:

1. Heart failure: When the heart is unable to pump blood effectively, it can lead to a backup of fluid in the lungs, causing pulmonary edema.

2. Kidney failure: If the kidneys are not functioning properly, they may not be able to remove excess fluid from the body, leading to fluid buildup in the lungs.

3. Infections: Pneumonia or other infections in the lungs can cause inflammation and fluid leakage into the air sacs, resulting in pulmonary edema.

4. High altitude: Exposure to high altitudes can lead to a condition known as high-altitude pulmonary edema, where the decreased oxygen levels cause fluid to leak into the lungs.

5. Inhalation of toxic substances: Inhaling toxic fumes or smoke can damage the lungs and lead to pulmonary edema.

Overall, pulmonary edema occurs when there is an imbalance between the amount of fluid entering the lungs and the ability of the lungs to remove it, resulting in fluid accumulation and difficulty breathing.
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Google Gemini AI
more than 2 weeks ago
Pulmonary Edema: Causes and Mechanism

Pulmonary edema is a condition characterized by fluid accumulation in the airspaces of the lungs. It can be caused by various mechanisms that disrupt the normal fluid balance in the lungs.

1. Increased Hydrostatic Pressure in Pulmonary Capillaries:

- The most common cause of pulmonary edema is elevated pressure in the pulmonary capillaries (blood vessels in the lungs).
- This can occur due to conditions such as:
- Left-sided heart failure: The weakened heart cannot pump blood effectively, leading to backward pressure in the pulmonary veins and capillaries.
- Valvular heart disease: Obstructed or leaky heart valves hinder blood flow, increasing capillary pressure.

2. Decreased Plasma Osmotic Pressure:

- Albumin, the main protein in blood plasma, is a key factor in maintaining fluid balance.
- Conditions that decrease plasma albumin levels, such as severe protein malnutrition, liver disease, and nephrotic syndrome, reduce the osmotic pressure in the blood.
- This causes fluid to leak out of the capillaries into the lung tissue.

3. Increased Capillary Permeability:

- Damage to the capillary walls can lead to increased leakage of fluid into the interstitium (spaces between the air sacs).
- This can occur due to:
- Inflammation or infection (e.g., pneumonia)
- Certain drugs (e.g., aspirin overdose)
- Inhalational injuries (e.g., smoke inhalation)

4. Impaired Lymphatic Drainage:

- The lymphatic system helps drain excess fluid from the lungs.
- Obstruction or blockage of the lymphatic vessels can result in fluid accumulation.

Mechanism of Fluid Accumulation:

- When hydrostatic pressure or capillary permeability increases, or plasma osmotic pressure decreases, an imbalance occurs.
- Fluid shifts from the capillaries into the interstitium and eventually into the air sacs.
- This fluid accumulation interferes with gas exchange, causing shortness of breath, coughing, and potentially life-threatening respiratory distress.
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