Differentiate between compensated and decompensated cirrhosis?
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Apr 24
Compensated cirrhosis refers to a stage of liver disease where the liver is still able to function relatively well despite the presence of scarring and damage. In compensated cirrhosis, the liver is able to perform its essential functions, such as producing proteins, processing nutrients, and detoxifying the blood. Patients with compensated cirrhosis may not exhibit any symptoms or may only have mild symptoms such as fatigue or abdominal discomfort.
Decompensated cirrhosis, on the other hand, refers to a more advanced stage of liver disease where the liver is no longer able to function properly. In decompensated cirrhosis, the liver is unable to perform its essential functions, leading to a buildup of toxins in the blood and a variety of serious complications. Symptoms of decompensated cirrhosis may include jaundice, ascites (fluid buildup in the abdomen), hepatic encephalopathy (confusion and cognitive impairment), and gastrointestinal bleeding. Decompensated cirrhosis is considered a medical emergency and requires immediate treatment.
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Google Gemini AI
Apr 24
Compensated Cirrhosis
- Definition: A stage of cirrhosis characterized by intact liver function despite scarring and fibrosis. - Liver Function: Normal or slightly impaired liver function tests, minimal or no jaundice, and no signs of portal hypertension. - Clinical Features: Asymptomatic or minimal fatigue and discomfort. - Treatment: Focus on preventing disease progression, includes lifestyle modifications (e.g., avoiding alcohol, maintaining a healthy weight), managing underlying cause (e.g., hepatitis C antiviral therapy), and monitoring for complications.
Decompensated Cirrhosis
- Definition: A stage of cirrhosis characterized by severe liver dysfunction and clinical complications. - Liver Function: Markedly impaired liver function tests, significant jaundice, and signs of portal hypertension (e.g., ascites, encephalopathy, variceal bleeding). - Clinical Features: Symptoms include fatigue, jaundice, abdominal swelling, confusion, and gastrointestinal bleeding. - Treatment: Requires more aggressive management to prevent life-threatening complications. Includes medications (e.g., diuretics, lactulose), endoscopic interventions (e.g., variceal band ligation), and liver transplantation as a potential last resort.