The thyroid gland is a small, butterfly-shaped gland located in the front of the neck, just below the Adam's apple. It plays a crucial role in regulating the body's metabolism by producing hormones that control how the body uses energy. The thyroid gland produces two main hormones, thyroxine (T4) and triiodothyronine (T3), which help regulate heart rate, blood pressure, body temperature, and weight.
The thyroid gland is controlled by the pituitary gland, which releases thyroid-stimulating hormone (TSH) to signal the thyroid to produce more hormones when needed. If the thyroid gland is not functioning properly, it can lead to conditions such as hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid), which can cause a range of symptoms including fatigue, weight gain or loss, and changes in mood.
Overall, the thyroid gland plays a vital role in maintaining the body's overall health and well-being.
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Google Gemini AI
1 day ago
Structure:
- Located in the neck, just below the larynx (voice box) - Consists of two connected lobes, one on either side of the trachea - Weighs approximately 15-30 grams in adults
Histology:
- Composed of follicles lined by epithelial cells - Follicles contain a gelatinous substance called colloid, which stores thyroid hormones - C cells, located in the parafollicular region, produce calcitonin, a hormone involved in calcium metabolism
Function:
- Produces and releases thyroid hormones: - Thyroxine (T4): primary hormone, regulates metabolism - Triiodothyronine (T3): more potent than T4, also regulates metabolism - Thyroid hormones regulate: - Growth and development - Metabolism (energy production) - Heart rate - Body temperature - Cognitive function - Reproduction
Regulation of Thyroid Hormone Production:
- Thyroid-stimulating hormone (TSH) from the pituitary gland stimulates thyroid hormone production - Thyrotropin-releasing hormone (TRH) from the hypothalamus stimulates TSH production - Negative feedback loop: Thyroid hormones inhibit the production of TSH and TRH, maintaining hormone levels
Clinical Significance:
- Hypothyroidism: deficiency of thyroid hormones, leading to symptoms such as weight gain, fatigue, and depression - Hyperthyroidism: excess thyroid hormones, resulting in weight loss, anxiety, and rapid heart rate - Thyroid nodules: non-cancerous or cancerous growths in the thyroid gland - Thyroid cancer: can occur in any age group, but is most common in middle-aged women