Describe the cause , differential diagnoses of Tuberculosis?
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May 10
Tuberculosis (TB) is a bacterial infection caused by Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other parts of the body such as the kidneys, spine, and brain. TB is spread through the air when an infected person coughs or sneezes, and it is more likely to spread in crowded or poorly ventilated environments.
Differential diagnoses of TB include:
1. Pneumonia: Both TB and pneumonia can cause symptoms such as cough, fever, and difficulty breathing. However, pneumonia is usually caused by a virus or bacteria other than Mycobacterium tuberculosis.
2. Lung cancer: TB can cause symptoms such as coughing up blood and chest pain, which are also common symptoms of lung cancer. Imaging tests such as chest X-rays or CT scans can help differentiate between the two conditions.
3. Bronchitis: TB and bronchitis can both cause a persistent cough, but bronchitis is usually caused by a viral infection and does not typically cause weight loss or night sweats.
4. Sarcoidosis: This is a rare inflammatory disease that can affect the lungs and other organs. Symptoms of sarcoidosis can be similar to TB, but the two conditions have different underlying causes and require different treatments.
5. Pneumothorax: This is a condition in which air leaks into the space between the lungs and the chest wall, causing the lung to collapse. Symptoms can include chest pain and shortness of breath, which can be similar to symptoms of TB.
It is important to consult a healthcare provider for an accurate diagnosis and appropriate treatment if TB is suspected. Testing for TB may involve a physical exam, imaging tests, and laboratory tests such as sputum culture or a tuberculin skin test.
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Google Gemini AI
May 10
Cause:
- Tuberculosis (TB) is a bacterial infection caused by the bacterium -Mycobacterium tuberculosis-.
Differential Diagnoses:
- Pulmonary TB: - Other bacterial infections (pneumonia, bronchitis) - Viral infections (respiratory syncytial virus, influenza) - Fungal infections (pneumocystis pneumonia) - Lung cancer - Extrapulmonary TB: - Lymph node TB: Enlarged lymph nodes, especially in the neck or chest - Skeletal TB: Joint and bone pain, spinal deformities - Genitourinary TB: Urinary tract symptoms, infertility - Gastrointestinal TB: Abdominal pain, diarrhea, weight loss - Central nervous system TB: Meningitis, encephalitis - Other: Skin TB, ocular TB
Additional Considerations:
- Comorbidities that increase risk of TB: HIV infection, diabetes, immunosuppression - Environmental and social factors: Crowded living conditions, poverty, poor nutrition - Travel history: Recent travel to high-burden countries - Occupational exposure: Healthcare professionals, prison inmates - Latent TB infection: Individuals infected with -M. tuberculosis- but without active disease - PPD skin test or interferon-gamma release assay (IGRA) blood test can be used to diagnose latent TB - Treatment of latent TB can prevent development of active disease later on