Describe eight uses of transition elements in pharmacy?
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Aug 15
1. Catalysis: Transition metals such as platinum, palladium, and ruthenium are used as catalysts in various pharmaceutical reactions, including hydrogenation, oxidation, and reduction reactions.
2. Drug delivery: Transition metals can be used to design drug delivery systems that target specific tissues or cells in the body, improving the efficacy and reducing side effects of pharmaceutical drugs.
3. Imaging agents: Transition metals like gadolinium and technetium are used as contrast agents in medical imaging techniques such as MRI and nuclear medicine scans to enhance the visibility of tissues and organs.
4. Anticancer drugs: Transition metal complexes are used in the development of anticancer drugs, such as cisplatin and carboplatin, which are commonly used in chemotherapy to treat various types of cancer.
5. Antimicrobial agents: Transition metal complexes have shown promising antimicrobial properties and are being explored as potential alternatives to traditional antibiotics for treating bacterial infections.
6. Antioxidants: Transition metals like selenium and zinc are essential components of antioxidant enzymes that help protect cells from oxidative damage and reduce the risk of chronic diseases.
7. Metal chelation therapy: Transition metal chelators, such as EDTA and DMSA, are used in the treatment of heavy metal poisoning by binding to toxic metals in the body and facilitating their excretion.
8. Diagnostic tests: Transition metals are used in diagnostic tests for various medical conditions, such as measuring blood glucose levels using glucose meters that contain platinum electrodes.
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Google Gemini AI
Aug 15
1. Antiseptic and Disinfectant: - Silver (Ag) in silver nitrate is used as an antiseptic in eye drops and dressings. - Zinc (Zn) in zinc oxide is used as a disinfectant in ointments and diaper creams.
2. Antibacterial and Antifungal: - Gold (Au) in gold sodium thiomalate used to treat rheumatoid arthritis has antibacterial properties. - Copper (Cu) in copper undecylenate is used as an antifungal agent in creams and lotions.
3. Radiological Contrast Agents: - Iodine (I) in iodine-based contrast agents is used for X-ray imaging of blood vessels and organs. - Gadolinium (Gd) is used as a contrast agent for magnetic resonance imaging (MRI).
4. Cancer Therapeutics: - Platinum (Pt) in cisplatin and carboplatin are used as chemotherapy drugs to treat various cancers. - Iron (Fe) in iron chelators is used to reduce iron overload in patients with blood disorders.
5. Anti-inflammatory and Immunosuppressant: - Gold (Au) in gold compounds is used to treat rheumatoid arthritis. - Zinc (Zn) in zinc acetate is used to reduce inflammation in the eyes.
6. Vitamin Supplements: - Iron (Fe) is an essential component of hemoglobin and used as an iron supplement. - Chromium (Cr) is involved in glucose metabolism and used in supplements for diabetes management.
7. Enzyme Cofactors: - Zinc (Zn) is a cofactor for many enzymes involved in metabolism and cell signaling. - Copper (Cu) is a cofactor for enzymes involved in oxygen transport and antioxidant defense.
8. Pharmaceuticals Synthesized Using Transition Metal Catalysts: - Transition metals, such as palladium (Pd) and rhodium (Rh), are used as catalysts in the synthesis of various pharmaceuticals, including statins, antipsychotics, and antibiotics.