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Anonymous
1 day ago

Advantage of parenteral route?

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ChatGPT
1 day ago
1. Rapid onset of action: Parenteral administration allows drugs to bypass the digestive system and be directly absorbed into the bloodstream, leading to a quicker onset of action compared to oral administration.

2. Higher bioavailability: By avoiding first-pass metabolism in the liver, parenteral administration can result in higher bioavailability of the drug, meaning a larger proportion of the drug reaches the systemic circulation.

3. Precise dosing: Parenteral administration allows for more accurate dosing of medications, as the entire dose is delivered directly into the bloodstream.

4. Useful in patients with gastrointestinal issues: Parenteral administration is particularly useful in patients who have difficulty swallowing or have gastrointestinal issues that may affect the absorption of oral medications.

5. Suitable for unconscious or uncooperative patients: Parenteral administration can be used in patients who are unconscious or unable to take medications orally, ensuring they receive the necessary treatment.
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Google Gemini AI
1 day ago
- Rapid onset of action: Parenteral administration bypasses the gastrointestinal tract, allowing the drug to reach the bloodstream directly. This is particularly advantageous for drugs that need to take effect quickly, such as antibiotics, pain relievers, and anesthesia.
- Controlled dosage: Parenteral administration allows for precise control of the drug dosage, as the drug is administered directly into the bloodstream. This is important for drugs that have a narrow therapeutic index, such as chemotherapeutic agents.
- Avoidance of gastrointestinal side effects: Drugs that are administered parenterally do not have to pass through the gastrointestinal tract, which can avoid side effects such as nausea, vomiting, and diarrhea. This is especially important for patients who have a sensitive stomach or who are taking multiple medications.
- Bypass of hepatic first-pass metabolism: The liver is responsible for metabolizing many drugs before they reach the bloodstream. Parenteral administration bypasses this process, allowing the drug to reach the bloodstream in its active form. This is important for drugs that are extensively metabolized in the liver.
- Direct delivery to target site: Some parenteral routes, such as intrathecal injection, allow for the direct delivery of drugs to a specific target site. This is useful for drugs that are intended to act on the central nervous system or on a specific organ.
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