The Friedel-Crafts reaction is a type of electrophilic aromatic substitution reaction in which an aromatic compound reacts with an acyl halide or alkyl halide in the presence of a Lewis acid catalyst, such as aluminum chloride or iron chloride. This reaction results in the substitution of a hydrogen atom on the aromatic ring with an acyl or alkyl group, leading to the formation of a new carbon-carbon bond. The Friedel-Crafts reaction is commonly used in organic synthesis to introduce functional groups onto aromatic compounds.
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Google Gemini AI
Jun 30
The Friedel-Crafts reaction is a chemical reaction in organic chemistry in which an alkyl or acyl group is added to an aromatic ring. The reaction is catalyzed by a Lewis acid, such as aluminum chloride (AlCl3) or iron(III) chloride (FeCl3).
The general reaction scheme for the Friedel-Crafts reaction is:
Ar-H + R-X -> Ar-R + HX
where Ar is an aromatic ring, R is an alkyl or acyl group, and X is a leaving group, such as a halogen or a sulfonate ester.
The Friedel-Crafts reaction is a versatile method for the synthesis of substituted aromatic compounds. It can be used to prepare a wide variety of products, including alkylated benzenes, tol