Captopril is an angiotensin-converting enzyme (ACE) inhibitor, which works by blocking the conversion of angiotensin I to angiotensin II. This leads to vasodilation and decreased blood pressure. However, one of the side effects of ACE inhibitors like captopril is a dry cough.
The exact mechanism behind this side effect is not fully understood, but it is believed to be related to the accumulation of bradykinin in the lungs. Bradykinin is a substance that causes inflammation and irritation in the respiratory tract, leading to a persistent dry cough in some individuals taking ACE inhibitors.
It is important to note that not everyone who takes captopril will experience a dry cough, but it is a known side effect of this medication. If you develop a persistent cough while taking captopril, it is important to speak with your healthcare provider to discuss alternative treatment options.