The persecution of Christians began in the early days of the Christian faith, with the Roman Empire being one of the first major powers to actively persecute Christians. The first widespread persecution of Christians by the Roman Empire began in the 1st century AD under Emperor Nero, and continued intermittently for several centuries until the Edict of Milan in 313 AD, which granted religious tolerance to Christians. Persecution of Christians has continued throughout history in various forms and in different parts of the world.