Blood groups are defined by the presence or absence of specific antigens on the surface of red blood cells. These antigens are genetically determined and inherited from both parents. There are several different blood group systems, but the ABO system is the most important one in terms of blood transfusions.
ABO Blood Group System
The ABO blood group system is based on the presence or absence of two antigens, A and B. People can have type A blood, type B blood, type AB blood, or type O blood.
- Type A blood: Has A antigens on the red blood cells.
- Type B blood: Has B antigens on the red blood cells.
- Type AB blood: Has both A and B antigens on the red blood cells.
- Type O blood: Has neither A nor B antigens on the red blood cells.
Rh (Rhesus) Factor
In addition to the ABO blood group system, there is also the Rh factor. The Rh factor is a protein that is present on the surface of red blood cells in most people. People who have the Rh factor are said to be Rh-positive, while those who do not have the Rh factor are said to be Rh-negative.
Blood Transfusions
When a blood transfusion is necessary, it is important to match the donor's blood group to the recipient's blood group. If the blood groups are not compatible, the recipient's immune system will attack the donor's red blood cells, which can lead to a dangerous condition called hemolytic transfusion reaction.
Blood Type Compatibility
The table below shows which blood types can receive blood transfusions from which other blood types.
| Recipient's Blood Type | Compatible Donor Blood Types |
|---|---|
| A+ | A+, A-, O+, O- |
| A- | A-, O- |
| B+ | B+, B-, O+, O- |
| B- | B-, O- |
| AB+ | A+, A-, B+, B-, O+, O- |
| AB- | A-, B-, O- |
| O+ | O+, O- |
| O- | O- |
It is important to note that the Rh factor must also be compatible for a blood transfusion to be successful.