What is a nuclear receptor?

A nuclear receptor is a protein found within cells that is responsible for sensing and responding to various molecules, including hormones, vitamins, and other signaling molecules. When these molecules bind to the nuclear receptor, it triggers a series of events that regulate gene expression and ultimately control various physiological processes within the cell. Nuclear receptors play a crucial role in many biological processes, including metabolism, development, and immune response.

A nuclear receptor is a type of protein that binds to a specific DNA sequence and regulates gene expression. Nuclear receptors are classified as either ligand-activated or constitutively active. Ligand-activated nuclear receptors bind to a specific ligand, which then causes the receptor to undergo a conformational change and bind to DNA. Constitutively active nuclear receptors do not require a ligand to bind to DNA.

Nuclear receptors play a role in a variety of cellular processes, including metabolism, development, and reproduction. They are also involved in the regulation of the immune system and the response to stress.