The time frame of human evolution is believed to have started around 6-7 million years ago with the divergence of the human lineage from that of our closest living relatives, the chimpanzees. The earliest known species in the human lineage, Ardipithecus ramidus, lived around 4.4 million years ago. The genus Homo, which includes modern humans, is believed to have emerged around 2-3 million years ago. The first anatomically modern humans, Homo sapiens, appeared around 300,000 years ago. It is important to note that the exact timeline of human evolution is still a topic of ongoing research and debate among scientists.