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Jan 4

Structure and types of neurons-Resting membrane potential,action potential, impulse transmission through myelinated and unmyelinated nerve fibres and types of neurotransmitter:- mechanism of neuro?

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Jan 4
Structure and Types of Neurons:
Neurons are the basic building blocks of the nervous system. They are specialized cells that transmit information through electrical and chemical signals. Neurons have three main parts: the cell body, dendrites, and axon. The cell body contains the nucleus and other organelles necessary for the neuron's functioning. Dendrites are branched extensions that receive signals from other neurons. The axon is a long, slender projection that carries signals away from the cell body.

There are three main types of neurons based on their function:
1. Sensory Neurons: These neurons transmit sensory information from sensory organs (such as the eyes, ears, and skin) to the central nervous system (CNS).
2. Motor Neurons: These neurons transmit signals from the CNS to muscles and glands, enabling movement and secretion.
3. Interneurons: These neurons are found within the CNS and facilitate communication between sensory and motor neurons.

Resting Membrane Potential:
Resting membrane potential refers to the electrical potential difference across the membrane of a neuron when it is at rest. It is typically around -70 millivolts (mV) and is maintained by the unequal distribution of ions across the neuron's membrane. The resting membrane potential is primarily influenced by the movement of potassium (K+) and sodium (Na+) ions through ion channels.

Action Potential:
An action potential is a rapid and brief change in the electrical potential of a neuron's membrane. It occurs when the neuron is stimulated and reaches a certain threshold. The action potential involves a depolarization phase, where the membrane potential becomes more positive, followed by a repolarization phase, where the membrane potential returns to its resting state. This electrical signal allows for the transmission of information along the neuron.

Impulse Transmission through Myelinated and Unmyelinated Nerve Fibers:
Nerve fibers can be myelinated or unmyelinated. Myelin is a fatty substance that wraps around the axon of some neurons, forming a protective sheath. In myelinated nerve fibers, the myelin acts as an insulator, preventing the leakage of ions and increasing the speed of impulse transmission. The action potential "jumps" from one node of Ranvier (unmyelinated region) to another, a process known as saltatory conduction. This allows for faster transmission of the impulse.

In unmyelinated nerve fibers, the action potential propagates continuously along the entire length of the axon. However, the speed of transmission is slower compared to myelinated fibers.

Types of Neurotransmitters:
Neurotransmitters are chemical messengers that transmit signals between neurons or from neurons to other cells (such as muscles or glands). There are several types of neurotransmitters, including:

1. Acetylcholine: Involved in muscle contraction, learning, and memory.
2. Dopamine: Regulates movement, motivation, and reward.
3. Serotonin: Regulates mood, appetite, and sleep.
4. GABA (Gamma-Aminobutyric Acid): Inhibitory neurotransmitter that reduces neuronal activity.
5. Glutamate: Excitatory neurotransmitter that enhances neuronal activity.
6. Norepinephrine: Involved in the "fight or flight" response and mood regulation.

Mechanism of Neurotransmission:
Neurotransmission occurs through a series of steps. When an action potential reaches the presynaptic terminal of a neuron, it triggers the release of neurotransmitters into the synaptic cleft. The neurotransmitters then bind to specific receptors on the postsynaptic neuron, initiating a response. This response can either be excitatory, leading to depolarization and increased likelihood of an action potential, or inhibitory, leading to hyperpolarization and decreased likelihood of an action potential. The neurotransmitters are then either broken down by enzymes or reabsorbed by the presynaptic neuron through a process called reuptake, terminating the signal.
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