State the criteria for diagnosis of rhematic fever?

The criteria for the diagnosis of rheumatic fever include:

1. Evidence of a preceding group A streptococcal infection, such as a positive throat culture or rapid strep test, or elevated streptococcal antibody titers.
2. Presence of two major criteria or one major criterion and two minor criteria:
Major criteria:
- Carditis (inflammation of the heart)
- Polyarthritis (inflammation of multiple joints)
- Chorea (involuntary movements)
- Erythema marginatum (a rash)
- Subcutaneous nodules (small, firm lumps under the skin)
Minor criteria:
- Fever
- Arthralgia (joint pain)
- Elevated acute phase reactants (e.g. ESR, CRP)
- Prolonged PR interval on ECG

A diagnosis of rheumatic fever is made if the patient meets the criteria outlined above and does not have an alternative explanation for their symptoms. It is important to note that the diagnosis of rheumatic fever is primarily clinical and there is no specific test that can definitively confirm the diagnosis.

Jones Criteria (Modified)

Major Criteria:
- Carditis (first manifestation)
- Polyarthritis (involving at least 5 joints)
- Chorea (involuntary, purposeless movements)

Minor Criteria:
- Fever (temperature >101°F)
- Arthralgia (joint pain)
- Erythema marginatum (circinate rash)
- Subcutaneous nodules (hard, painless bumps)
- Previous rheumatic fever or chorea

Supporting Laboratory Findings:
- Increased erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP)
- Evidence of streptococcal infection (positive throat culture or elevated antistreptolysin-O titer)

Diagnosis:

- Definitive: Two major criteria or one major criterion and two minor criteria
- Probable: One major criterion and one minor criterion
- Possible: Two or more minor criteria, supported by laboratory findings