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Jun 28
1. Follow the prescribed dosage and duration of treatment as directed by your healthcare provider.
2. Inform your healthcare provider about any allergies or medical conditions you have before starting antifungal treatment.
3. Avoid consuming alcohol while taking antifungal medications, as it can increase the risk of side effects.
4. Be cautious when driving or operating machinery, as some antifungal medications can cause dizziness or drowsiness.
5. Monitor for any signs of allergic reactions, such as rash, itching, swelling, or difficulty breathing, and seek medical attention immediately if they occur.
6. Inform your healthcare provider about any other medications or supplements you are taking, as they may interact with antifungal medications.
7. Store antifungal medications in a cool, dry place away from direct sunlight and out of reach of children.
8. Do not share antifungal medications with others, as they are prescribed based on individual needs and conditions.
2. Inform your healthcare provider about any allergies or medical conditions you have before starting antifungal treatment.
3. Avoid consuming alcohol while taking antifungal medications, as it can increase the risk of side effects.
4. Be cautious when driving or operating machinery, as some antifungal medications can cause dizziness or drowsiness.
5. Monitor for any signs of allergic reactions, such as rash, itching, swelling, or difficulty breathing, and seek medical attention immediately if they occur.
6. Inform your healthcare provider about any other medications or supplements you are taking, as they may interact with antifungal medications.
7. Store antifungal medications in a cool, dry place away from direct sunlight and out of reach of children.
8. Do not share antifungal medications with others, as they are prescribed based on individual needs and conditions.
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Google Gemini AI
Jun 28
Precautions of Antifungals
General Precautions:
- Allergic reactions: Patients with known allergies to azoles, polyenes, or echinocandins should avoid using those classes.
- Hematological effects: Azoles (especially voriconazole) can cause bone marrow suppression (neutropenia, thrombocytopenia, anemia). Monitor blood counts regularly.
- Hepatotoxicity: Azoles (especially itraconazole) can cause liver damage. Monitor liver function tests (LFTs) regularly.
- Renal impairment: Some antifungals (e.g., amphotericin B) can cause nephrotoxicity. Monitor renal function closely.
- Drug interactions: Antifungals can interact with many other medications (e.g., anticoagulants, immunosuppressants). Consult a healthcare professional before taking any new medications while on antifungals.
Specific Precautions:
Amphotericin B:
- Nephrotoxicity: A major concern, especially with high doses. Monitor renal function closely.
- Hypokalemia: Can lead to muscle weakness and cardiac arrhythmias. Supplement potassium if necessary.
- Thrombophlebitis: Administer through a large vein with saline flushes to prevent vein irritation.
Azoles:
- Liver toxicity: Monitor LFTs regularly.
- Drug interactions: Can interact with many other medications, including warfarin, cyclosporine, and tacrolimus.
- Long-term use: May increase the risk of liver damage and adrenal insufficiency.
Polyenes:
- Nephrotoxicity: Can cause acute kidney injury. Monitor renal function closely.
- Hypokalemia: Can lead to muscle weakness and cardiac arrhythmias. Supplement potassium if necessary.
- Phlebitis: Administer through a central line to avoid peripheral vein irritation.
Echinocandins:
- Hepatotoxicity: Rare, but monitor LFTs if patient has liver disease.
- Drug interactions: Can interact with some immunosuppressants (e.g., tacrolimus).
Other Precautions:
- Fungal resistance: Monitor patients for signs of resistance and adjust treatment accordingly.
- Immune suppression: Antifungals can suppress the immune system, increasing the risk of opportunistic infections.
- Pregnancy and breastfeeding: Some antifungals (e.g., fluconazole) are safe during pregnancy. Discuss with a healthcare professional before using antifungals while pregnant or breastfeeding.
- Driving and operating machinery: Some antifungals (e.g., voriconazole) can cause dizziness or blurred vision. Use caution when driving or operating machinery.
General Precautions:
- Allergic reactions: Patients with known allergies to azoles, polyenes, or echinocandins should avoid using those classes.
- Hematological effects: Azoles (especially voriconazole) can cause bone marrow suppression (neutropenia, thrombocytopenia, anemia). Monitor blood counts regularly.
- Hepatotoxicity: Azoles (especially itraconazole) can cause liver damage. Monitor liver function tests (LFTs) regularly.
- Renal impairment: Some antifungals (e.g., amphotericin B) can cause nephrotoxicity. Monitor renal function closely.
- Drug interactions: Antifungals can interact with many other medications (e.g., anticoagulants, immunosuppressants). Consult a healthcare professional before taking any new medications while on antifungals.
Specific Precautions:
Amphotericin B:
- Nephrotoxicity: A major concern, especially with high doses. Monitor renal function closely.
- Hypokalemia: Can lead to muscle weakness and cardiac arrhythmias. Supplement potassium if necessary.
- Thrombophlebitis: Administer through a large vein with saline flushes to prevent vein irritation.
Azoles:
- Liver toxicity: Monitor LFTs regularly.
- Drug interactions: Can interact with many other medications, including warfarin, cyclosporine, and tacrolimus.
- Long-term use: May increase the risk of liver damage and adrenal insufficiency.
Polyenes:
- Nephrotoxicity: Can cause acute kidney injury. Monitor renal function closely.
- Hypokalemia: Can lead to muscle weakness and cardiac arrhythmias. Supplement potassium if necessary.
- Phlebitis: Administer through a central line to avoid peripheral vein irritation.
Echinocandins:
- Hepatotoxicity: Rare, but monitor LFTs if patient has liver disease.
- Drug interactions: Can interact with some immunosuppressants (e.g., tacrolimus).
Other Precautions:
- Fungal resistance: Monitor patients for signs of resistance and adjust treatment accordingly.
- Immune suppression: Antifungals can suppress the immune system, increasing the risk of opportunistic infections.
- Pregnancy and breastfeeding: Some antifungals (e.g., fluconazole) are safe during pregnancy. Discuss with a healthcare professional before using antifungals while pregnant or breastfeeding.
- Driving and operating machinery: Some antifungals (e.g., voriconazole) can cause dizziness or blurred vision. Use caution when driving or operating machinery.
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