Anonymous
Nov 10
Outline the secondary changes that occur in fibroids.
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Nov 10
1. Compression of surrounding structures: As fibroids grow in size, they can compress nearby organs and structures such as the bladder, causing urinary symptoms like frequent urination or difficulty emptying the bladder. They can also compress the rectum, leading to constipation or difficulty passing stool.
2. Distortion of the uterine cavity: Large fibroids can distort the shape of the uterus, leading to abnormal uterine bleeding, pelvic pain, and infertility. This distortion can also affect the ability of the uterus to contract effectively during menstruation, leading to heavy or prolonged periods.
3. Changes in hormone levels: Fibroids can alter the normal hormonal balance in the body, leading to symptoms such as irregular menstrual cycles, heavy bleeding, and pelvic pain. They can also affect the production and metabolism of hormones like estrogen and progesterone, which can further exacerbate symptoms.
4. Impact on fertility: Fibroids can affect fertility by interfering with the implantation of a fertilized egg in the uterus or by blocking the fallopian tubes. They can also cause complications during pregnancy, such as miscarriage, preterm labor, or abnormal fetal positioning.
5. Psychological impact: The physical symptoms and potential impact on fertility associated with fibroids can also have a significant psychological impact on individuals, leading to feelings of anxiety, depression, and stress. This can further exacerbate the overall burden of the condition on a person's quality of life.
2. Distortion of the uterine cavity: Large fibroids can distort the shape of the uterus, leading to abnormal uterine bleeding, pelvic pain, and infertility. This distortion can also affect the ability of the uterus to contract effectively during menstruation, leading to heavy or prolonged periods.
3. Changes in hormone levels: Fibroids can alter the normal hormonal balance in the body, leading to symptoms such as irregular menstrual cycles, heavy bleeding, and pelvic pain. They can also affect the production and metabolism of hormones like estrogen and progesterone, which can further exacerbate symptoms.
4. Impact on fertility: Fibroids can affect fertility by interfering with the implantation of a fertilized egg in the uterus or by blocking the fallopian tubes. They can also cause complications during pregnancy, such as miscarriage, preterm labor, or abnormal fetal positioning.
5. Psychological impact: The physical symptoms and potential impact on fertility associated with fibroids can also have a significant psychological impact on individuals, leading to feelings of anxiety, depression, and stress. This can further exacerbate the overall burden of the condition on a person's quality of life.
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Google Gemini AI
Nov 10
Secondary Changes in Fibroids
1. Degeneration
- Hyaline degeneration: Loss of nuclei and cytoplasm, resulting in a glassy appearance.
- Cystic degeneration: Formation of fluid-filled spaces within the fibroid.
- Calcification: Deposition of calcium salts within the fibroid.
- Red degeneration (necrosis): Sudden loss of blood supply, leading to tissue death.
2. Infection
- Pyogenic infection: Bacterial invasion, causing inflammation and pus formation.
- Tuberculous infection: Infection with Mycobacterium tuberculosis.
3. Malignant Transformation
- Leiomyosarcoma: Rare but serious complication where fibroids transform into a cancerous tumor.
4. Atrophy
- Shrinkage of fibroids after menopause due to decreased estrogen levels.
5. Torsion
- Twisting of the fibroid on its pedicle, leading to impaired blood supply.
6. Incarceration
- Trapping of a fibroid within the pelvis or abdomen, causing pain and discomfort.
7. Intramural Extension
- Growth of fibroids into the uterine muscle wall, causing enlargement and distortion of the uterus.
8. Subserosal Extension
- Growth of fibroids on the outer surface of the uterus, potentially protruding into the abdominal cavity.
9. Submucosal Extension
- Growth of fibroids within the uterine lining, causing abnormal bleeding and infertility.
1. Degeneration
- Hyaline degeneration: Loss of nuclei and cytoplasm, resulting in a glassy appearance.
- Cystic degeneration: Formation of fluid-filled spaces within the fibroid.
- Calcification: Deposition of calcium salts within the fibroid.
- Red degeneration (necrosis): Sudden loss of blood supply, leading to tissue death.
2. Infection
- Pyogenic infection: Bacterial invasion, causing inflammation and pus formation.
- Tuberculous infection: Infection with Mycobacterium tuberculosis.
3. Malignant Transformation
- Leiomyosarcoma: Rare but serious complication where fibroids transform into a cancerous tumor.
4. Atrophy
- Shrinkage of fibroids after menopause due to decreased estrogen levels.
5. Torsion
- Twisting of the fibroid on its pedicle, leading to impaired blood supply.
6. Incarceration
- Trapping of a fibroid within the pelvis or abdomen, causing pain and discomfort.
7. Intramural Extension
- Growth of fibroids into the uterine muscle wall, causing enlargement and distortion of the uterus.
8. Subserosal Extension
- Growth of fibroids on the outer surface of the uterus, potentially protruding into the abdominal cavity.
9. Submucosal Extension
- Growth of fibroids within the uterine lining, causing abnormal bleeding and infertility.
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