- Sudden cessation of breathing for more than 20 seconds - Cyanosis (bluish discoloration of the skin) - Bradycardia (slow heart rate) - Hypotonia (low muscle tone) - Poor feeding or sucking - Lethargy or decreased responsiveness - Gasping or irregular breathing patterns - Apnea episodes may be accompanied by choking or gagging sounds - Episodes may occur during sleep or wakefulness - Risk factors for neonatal apnea include prematurity, low birth weight, respiratory infections, and maternal drug use during pregnancy.