How is syphilis treated in males? Which drugs are the best in managing it?

Syphilis in males is typically treated with antibiotics, most commonly with a single dose of benzathine penicillin G. Other antibiotics that may be used include doxycycline, tetracycline, or ceftriaxone.

The best drug for managing syphilis is benzathine penicillin G, as it is highly effective in treating the infection. It is important to follow the prescribed treatment regimen and complete the full course of antibiotics to ensure that the infection is completely eradicated. It is also important to abstain from sexual activity until the infection has been fully treated to prevent spreading it to others.

Treatment of Syphilis in Males

Early Syphilis (less than 1 year)

- Single intramuscular injection of benzathine penicillin G (2.4 million units)

Late Syphilis (more than 1 year)

- Benzathine penicillin G intramuscularly for 3 weeks (2.4 million units weekly)

Alternative Regimens for Those Allergic to Penicillin

- Doxycycline 100 mg orally twice daily for 14 days
- Azithromycin 500 mg orally once daily for 2 days

Best Drugs for Managing Syphilis

- Benzathine penicillin G is the most effective and recommended first-line treatment for all stages of syphilis.
- Doxycycline and azithromycin are alternative regimens for those allergic to penicillin, but they are less effective and may require longer treatment duration.

Important Notes:

- Treatment should be initiated as soon as possible after diagnosis.
- Follow-up serological testing is necessary to ensure treatment effectiveness.
- Sexual partners should also be tested and treated.
- Condom use should be continued until treatment is completed and serology is negative.