Haemophilia is a genetic disorder that affects the blood's ability to clot properly. It is caused by a mutation in one of the genes responsible for producing clotting factors, specifically factor VIII (haemophilia A) or factor IX (haemophilia B).
Haemophilia is not produced in a specific location, but rather it is a genetic condition that can be inherited from parents who carry the mutated gene. It is estimated that approximately 1 in 5,000 to 10,000 males are born with haemophilia worldwide.