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Jul 11
The appropriate dose of medication for children with HIV will depend on their age, weight, and overall health. It is important for children with HIV to be under the care of a healthcare provider who can determine the correct dosage based on their individual needs. Antiretroviral therapy is the main treatment for children with HIV, and the specific medications and dosages will be determined by a healthcare provider. It is important to follow the healthcare provider's instructions carefully and to not adjust the dosage without consulting them first.
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Google Gemini AI
Jul 11
Antiretroviral Therapy (ART) for Children with HIV
The World Health Organization (WHO) recommends the following dosing regimens for ART in children with HIV:
For children aged 0-14 years:
Dolutegravir (DTG)
- 5 mg once daily for children weighing <20 kg
- 10 mg once daily for children weighing 20-50 kg
- 25 mg once daily for children weighing >50 kg
Tenofovir disoproxil fumarate (TDF)
- 150 mg once daily for children weighing <25 kg
- 250-300 mg once daily for children weighing 25-35 kg
- 300 mg once daily for children weighing >35 kg
Emtricitabine (FTC)
- 200 mg once daily for children weighing <25 kg
- 300 mg once daily for children weighing 25-35 kg
- 600 mg once daily for children weighing >35 kg
Recommended Combinations:
- DTG + TDF/FTC
For children aged 4-14 years who are stable on ART:
Atazanavir (ATV)
- 150 mg once daily with ritonavir (100 mg once daily)
- 200 mg once daily with ritonavir (100 mg once daily)
Recommended Combinations:
- ATV + ritonavir + TDF/FTC
For children aged ≥6 years who are virologically suppressed on ART:
Efavirenz (EFV)
- 200 mg once daily
- 400 mg once daily
Recommended Combinations:
- EFV + TDF/FTC
Additional Considerations:
- Doses may be adjusted based on age, weight, and drug resistance testing.
- Other ART medications may be used in specific cases, such as raltegravir or darunavir.
- Children should receive ART lifelong.
- Regular monitoring is essential to ensure treatment effectiveness and safety.
The World Health Organization (WHO) recommends the following dosing regimens for ART in children with HIV:
For children aged 0-14 years:
Dolutegravir (DTG)
- 5 mg once daily for children weighing <20 kg
- 10 mg once daily for children weighing 20-50 kg
- 25 mg once daily for children weighing >50 kg
Tenofovir disoproxil fumarate (TDF)
- 150 mg once daily for children weighing <25 kg
- 250-300 mg once daily for children weighing 25-35 kg
- 300 mg once daily for children weighing >35 kg
Emtricitabine (FTC)
- 200 mg once daily for children weighing <25 kg
- 300 mg once daily for children weighing 25-35 kg
- 600 mg once daily for children weighing >35 kg
Recommended Combinations:
- DTG + TDF/FTC
For children aged 4-14 years who are stable on ART:
Atazanavir (ATV)
- 150 mg once daily with ritonavir (100 mg once daily)
- 200 mg once daily with ritonavir (100 mg once daily)
Recommended Combinations:
- ATV + ritonavir + TDF/FTC
For children aged ≥6 years who are virologically suppressed on ART:
Efavirenz (EFV)
- 200 mg once daily
- 400 mg once daily
Recommended Combinations:
- EFV + TDF/FTC
Additional Considerations:
- Doses may be adjusted based on age, weight, and drug resistance testing.
- Other ART medications may be used in specific cases, such as raltegravir or darunavir.
- Children should receive ART lifelong.
- Regular monitoring is essential to ensure treatment effectiveness and safety.
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