Differentiate between transtadial and transvarian transmission?
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May 9
Transtadial transmission refers to the transmission of a pathogen from one life stage of an arthropod vector to another life stage, such as from larva to nymph or nymph to adult. This type of transmission occurs within the same vector individual.
On the other hand, transovarian transmission refers to the transmission of a pathogen from an infected female arthropod vector to its offspring through the eggs. This type of transmission occurs between generations of vectors.
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Google Gemini AI
May 9
Transstadial Transmission
- Occurs when an arthropod vector acquires a pathogen during one developmental stage (e.g., larval stage) and transmits it during a subsequent stage (e.g., adult stage). - The pathogen remains within the vector's body and undergoes development or multiplication before being transmitted. - Example: Malaria parasite (Plasmodium spp.) in mosquitoes. Mosquitoes acquire the parasite in their larval stage and develop sporozoites (infective stage) in their salivary glands, which are transmitted to humans when the mosquito bites.
Transvarian Transmission
- Occurs when a pathogen is acquired by an arthropod vector during one stage of development (e.g., larval stage) and is transmitted to the vector's offspring (e.g., eggs). - The pathogen is present in the ovary of the female vector and is passed on to her eggs. - Example: Dengue virus in mosquitoes. Infected mosquitoes transmit the virus to their eggs, which develop into infected larvae. These larvae can grow into infected adult mosquitoes, which can then transmit the virus to humans.
Key Differences
- Timing: Transstadial transmission occurs within the same vector individual, while transvarian transmission occurs between generations of vectors. - Pathogen location: In transstadial transmission, the pathogen resides within the vector during its development, while in transvarian transmission, the pathogen is present in the vector's ovaries and eggs. - Significance: Transstadial transmission allows the pathogen to persist within the vector population, even during periods when transmission to humans is not occurring. Transvarian transmission ensures the continued presence of the pathogen in the vector population and can contribute to seasonal outbreaks.