Peptic ulcers are open sores that develop on the lining of the stomach, upper small intestine, or esophagus. They occur when the protective layer of mucus in these areas is weakened or damaged, allowing stomach acid to erode the tissues.
The main cause of peptic ulcers is a bacterial infection called Helicobacter pylori (H. pylori). This bacterium is commonly transmitted through contaminated food or water, and it weakens the protective lining of the stomach, making it more susceptible to damage from stomach acid. Other factors that can contribute to the development of peptic ulcers include long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen, excessive alcohol consumption, smoking, and stress.
There are two main types of peptic ulcers:
1. Gastric ulcers: These ulcers develop in the stomach lining and are typically caused by H. pylori infection or the use of NSAIDs. The pain associated with gastric ulcers usually worsens with eating.
2. Duodenal ulcers: These ulcers occur in the upper part of the small intestine, called the duodenum. They are the most common type of peptic ulcer and are often caused by H. pylori infection or excessive acid production. The pain from duodenal ulcers tends to improve with eating.
The major signs and symptoms of peptic ulcers include:
1. Abdominal pain: This is the most common symptom, typically described as a burning or gnawing sensation in the stomach area. The pain may come and go and can be relieved temporarily by eating or taking antacids.
2. Nausea and vomiting: Some individuals may experience these symptoms, especially if the ulcer is severe or bleeding.
3. Loss of appetite and weight loss: Chronic ulcers can lead to a decreased desire to eat, resulting in unintended weight loss.
4. Indigestion and bloating: These symptoms may occur after eating, as the stomach struggles to digest food properly.
The treatment of peptic ulcers involves a combination of medications and lifestyle changes. Medications commonly prescribed include proton pump inhibitors (PPIs) to reduce stomach acid production, antibiotics to eradicate H. pylori infection, and antacids to neutralize stomach acid. Lifestyle changes may include avoiding NSAIDs, reducing alcohol consumption, quitting smoking, managing stress levels, and adopting a healthy diet.
Prevention of peptic ulcers involves practicing good hygiene, such as washing hands thoroughly before eating, drinking clean water, and avoiding food from unhygienic sources. It is also important to limit the use of NSAIDs, especially without a prescription, and to seek medical attention if experiencing persistent symptoms suggestive of peptic ulcers. Additionally, getting tested and treated for H. pylori infection can help prevent the development of ulcers.