Collagen and other proteins of extracellular Matrix?

Collagen is the most abundant protein in the extracellular matrix, making up about 30% of the total protein in the human body. It provides structural support and strength to tissues and organs. Other proteins found in the extracellular matrix include elastin, fibronectin, laminin, and proteoglycans.

Elastin is a protein that allows tissues to stretch and recoil, providing elasticity to tissues such as skin, blood vessels, and lungs. Fibronectin is a glycoprotein that helps cells attach to the extracellular matrix and plays a role in cell migration and wound healing. Laminin is a glycoprotein that forms a network to which cells can attach, helping to maintain tissue structure and organization. Proteoglycans are proteins that are heavily glycosylated and help to maintain the hydration and compressibility of tissues.

Together, these proteins form a complex network in the extracellular matrix that provides structural support, regulates cell behavior, and plays a crucial role in tissue development, maintenance, and repair.