Bleeding of mice is a common procedure in research settings, particularly in studies involving the analysis of blood samples for various purposes such as measuring levels of certain substances, studying immune responses, or monitoring the effects of treatments or interventions. The procedure involves collecting a small amount of blood from the mouse, typically from the tail vein or the retro-orbital sinus, using a needle or lancet. It is important to follow proper protocols and guidelines to ensure the well-being and humane treatment of the animals.