The purpose of the message in the Safeguard commercial "Pabaon sa Buhay" is to emphasize the importance of protection and safeguarding one's health and well-being. The commercial aims to promote the idea that using Safeguard products can help protect individuals from germs and illnesses, ultimately ensuring a healthier and safer life. The message encourages viewers to prioritize their health and make safeguarding themselves a priority in their daily lives.