1. Rapid onset of action: IV administration allows for the direct delivery of medications or fluids into the bloodstream, resulting in a quick and immediate effect.
2. Precise control of dosage: IV administration allows for accurate and precise control over the dosage of medication or fluids being administered, ensuring that the desired therapeutic effect is achieved.
3. Higher bioavailability: IV administration bypasses the digestive system, avoiding the first-pass metabolism, which can lead to higher bioavailability of the drug compared to other routes of administration.
4. Suitable for patients unable to take oral medications: IV administration is particularly useful for patients who are unable to take medications orally, such as those who are unconscious, experiencing nausea or vomiting, or have difficulty swallowing.
5. Continuous administration: IV administration allows for continuous infusion of medications or fluids, which is beneficial in cases where a constant therapeutic level needs to be maintained, such as in anesthesia or critical care settings.
Disadvantages of intravenous (IV) administration:
1. Invasive procedure: IV administration requires the insertion of a needle or catheter into a vein, which can be uncomfortable and may cause pain or bruising at the injection site. It also carries a risk of infection or damage to the vein.
2. Requires healthcare professional: IV administration should be performed by a trained healthcare professional to ensure proper technique and minimize the risk of complications. This can limit the availability and accessibility of IV administration in certain settings.
3. Risk of adverse reactions: IV administration can lead to immediate and potentially severe adverse reactions, such as allergic reactions, anaphylaxis, or medication errors due to the rapid onset of action and direct delivery into the bloodstream.
4. Limited self-administration: Unlike oral medications, IV administration generally cannot be self-administered by patients, requiring them to rely on healthcare professionals for administration, which may limit convenience and independence.
5. Cost and resource-intensive: IV administration requires specialized equipment, supplies, and monitoring, making it more expensive and resource-intensive compared to other routes of administration. It may also require additional time and personnel for setup and monitoring.